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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PEX1 All Species: 21.21
Human Site: S1156 Identified Species: 29.17
UniProt: O43933 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43933 NP_000457.1 1283 142867 S1156 Q C L S A P S S M T Q D L P G
Chimpanzee Pan troglodytes XP_519198 1283 142803 S1156 Q C L S A P S S M T Q D L P G
Rhesus Macaque Macaca mulatta XP_001101055 1278 142022 S1151 Q C L S A P S S V T Q D L P G
Dog Lupus familis XP_532459 1267 140567 S1140 Q C L S A P S S T A Q D F S G
Cat Felis silvestris
Mouse Mus musculus Q5BL07 1284 141409 S1157 H C L S A P S S V T Q D L P A
Rat Rattus norvegicus P46462 806 89330 N680 E F L A K M T N G F S G A D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520628 1178 126535 S1050 S E L G S G T S P C P S S Q G
Chicken Gallus gallus XP_418655 1290 143066 I1164 C L S G P N S I T H D F T N I
Frog Xenopus laevis P23787 805 89193 T679 V D F L A K M T N G F S G A D
Zebra Danio Brachydanio rerio Q7ZU99 806 89405 N680 D F L A K M T N G F S G A D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KN62 801 88841 V675 D L T Y I A K V T Q G F S G A
Honey Bee Apis mellifera XP_397107 1069 120490 S943 K E L A T L T S G F T G A D L
Nematode Worm Caenorhab. elegans P54812 810 89622 T684 L N F L A K N T V G F S G A D
Sea Urchin Strong. purpuratus XP_797089 1508 166130 L1381 M T P A T P S L P P D T P L A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SCN8 815 90322 A689 Y T Q G F S G A D I T E I C Q
Baker's Yeast Sacchar. cerevisiae P24004 1043 117258 C917 G A D L Q G L C Y N A Y L K S
Red Bread Mold Neurospora crassa Q7SGP2 1381 148356 A1245 E G K Q I S T A Y F F D H Y A
Conservation
Percent
Protein Identity: 100 99.6 92.8 86.4 N.A. 82 23.3 N.A. 52.4 62.4 22.9 22.8 N.A. 23.6 27.6 22.1 35.2
Protein Similarity: 100 100 94.9 92 N.A. 89.5 39.2 N.A. 66 77.6 38.6 39 N.A. 37.6 46.7 38.4 53.2
P-Site Identity: 100 100 93.3 73.3 N.A. 80 6.6 N.A. 20 6.6 6.6 6.6 N.A. 0 13.3 6.6 13.3
P-Site Similarity: 100 100 100 73.3 N.A. 86.6 33.3 N.A. 33.3 6.6 13.3 26.6 N.A. 0 33.3 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. 23.5 25.7 21.4
Protein Similarity: N.A. N.A. N.A. 38.5 45.2 40.9
P-Site Identity: N.A. N.A. N.A. 0 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. 20 6.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 6 0 24 42 6 0 12 0 6 6 0 18 12 24 % A
% Cys: 6 30 0 0 0 0 0 6 0 6 0 0 0 6 0 % C
% Asp: 12 6 6 0 0 0 0 0 6 0 12 36 0 18 12 % D
% Glu: 12 12 0 0 0 0 0 0 0 0 0 6 0 0 0 % E
% Phe: 0 12 12 0 6 0 0 0 0 24 18 12 6 0 0 % F
% Gly: 6 6 0 18 0 12 6 0 18 12 6 18 12 6 30 % G
% His: 6 0 0 0 0 0 0 0 0 6 0 0 6 0 0 % H
% Ile: 0 0 0 0 12 0 0 6 0 6 0 0 6 0 6 % I
% Lys: 6 0 6 0 12 12 6 0 0 0 0 0 0 6 0 % K
% Leu: 6 12 53 18 0 6 6 6 0 0 0 0 30 6 18 % L
% Met: 6 0 0 0 0 12 6 0 12 0 0 0 0 0 0 % M
% Asn: 0 6 0 0 0 6 6 12 6 6 0 0 0 6 0 % N
% Pro: 0 0 6 0 6 36 0 0 12 6 6 0 6 24 0 % P
% Gln: 24 0 6 6 6 0 0 0 0 6 30 0 0 6 6 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 6 0 6 30 6 12 42 42 0 0 12 18 12 6 6 % S
% Thr: 0 12 6 0 12 0 30 12 18 24 12 6 6 0 0 % T
% Val: 6 0 0 0 0 0 0 6 18 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 6 0 0 6 0 0 0 0 12 0 0 6 0 6 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _